ProBio 12+

Point Detection of Biological Warfare Agents & Hazards

Detection Case
ProBio 12+
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CBRN Software

The Biodefence market requires a system to detect and identify biological warfare agents and hazards with the highest sensitivity, the highest selectivity, maximum speed and accuracy. OWR's ProBio 12+ is the first tool that combines these features for military, homeland security and biosafety applications.


  • Results within less than one hour after sample preparation
  • Parallel search (Multiplex) for different agents
  • Minimal detection limit
  • Lowest rate of false-positive results
  • Automated system
  • Independent from laboratory environment
  • No medical or biological specialist knowledge necessary


OWR's ProBio 12+
integrates nucleic acid tests (PCR) and immunoassays (ELISA) on one single platform. The user-friendly system enables quick point detection of the most relevant bacteria and toxins. Detection results provide the utmost level of reliability.

Currently the ProBio 12+ detects the following BWAs:

  • Bacillus anthracis, Francisella tularensis, Yersinia pestis, Botulinum Toxin, Rizin, Staphylococcus Enterotoxin B
  • Further applications, particularly for the detection of other organic hazards known as the "dirty dozen" are currently developed.
  • Virus tests upon request. 

Analysis Workflow

Sample collection, specific sample preparation and transfer of purified sample to ProBio Cartridge.

Cartridge transfer into the instrument.

Analysis Workflow

Test Methods

  • Amplification (PCR) for bacteria
  • Immunoassays (ELISA) for toxins

Sample preparation

ProBio 12+ Cartridge

All elements that are essential for the respective test are combined in a single disposable cartridge. The cartridge is a completely encased micro reactor. The cartridge concept supports implementation of nucleic acid base tests (PCR, Hybridization) and immunological test formats (ELISA). Detection is being carried out optically by the analysis of specific binding patterns on the integrated probe array.

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